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KMID : 0354420090370040210
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Medical Postgraduate
2009 Volume.37 No. 4 p.210 ~ p.214
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Pathologic Findings of Hepatic Injury Induced by Drugs and Toxins
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Jang Suk-Yong
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Abstract
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Many drugs and chemical agents can produce hepatic injury. Some are intrinsic toxins and others are idiosyncratic toxins. Drugs induce acute injury such as parenchymal damage and cholestasis, and also are an important cause of chronic hepatic diseases such as chronic hepatitis, fatty liver, cirrhosis and several vascular and neoplastic lesions. Most clinicians and pathologists should be aware of the potential drugs and other substances to cause acute and chronic liver lesions, and especially, pathologists should be familiar with histologic findings induced by hepatic toxins. This article deals with essential light microscopic findings of liver attributed to drugs and toxins.
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KEYWORD
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drugs and toxin, liver pathology
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